"Digitally enabled and virtual clinical trials offer the potential to increase the quality and efficiency of clinical trials-from reducing barriers to participation and improving the participant experience, to capturing more informative real-world data and lowering costs associated with conducting trials. CTTI's Digital Health Technologies recommendations and resources address the challenges that previously hindered the use of digital health technologies in clinical trials. With this new comprehensive guide, stakeholders across the clinical trials enterprise can start to benefit from the potential advantages of using digital health technologies, including capturing "real world" data from patients, reducing barriers to participation, and lowering costs." -- CLINICAL TRIALS TRANSFORMATION INITIATIVE